I found this while searching for the capsacium molecular structure: SCIENCE/HEALTH ABSTRACTS Vol. 5, No. 3 Copyright 1986 Phylis Austin CAPSAICIN TOXICITY Capsaicin, found in various hot peppers, has adverse effects on the peripheral nervous system. It also has adverse effects on several important centers in the brain, and on enzyme and neuroprotein function in the brain. Intestinal action on various nutrients, including protein, is altered to our injury. Furthermore, the blood vessels and heart are particularly sensitive to toxic factors in capsaicin. One dose of capsaicin is sufficient to destroy almost all substance P (an important nerve chemical related to endorphins) in the dorsal root ganglia of the nervous system, and causes about a 50 percent loss from part of the spinal cord. Loss of substance P may also lead to urinary retention, and because of the partial paralyzing effect on the bladder, is undoubtedly only part of why peppers irritate the bladder and prostate. Even low doses lead to low core body temperature (hypothermia), also due to a toxic influence on the brain. Capsaicin also interferes with glucose uptake, and at least one study suggests that it may cause cancer of the duodenum. (Nutrition Reviews 44(1)20-23, January, 1986) An earlier report (Anticancer Research 4:117-120, 1984) revealed the tumorigenic and mutagenic effect of capsaicin. What are we doing to ourselves!? hehehe -- ICQ at 15700349