Ya know I thought this was a no-brainer till I ran it through Google. Ya eat the heat/Ya suffer the consequences. All the dot/EDU's & Harvard & Yale & State .EDU stuff had my brain a spinnin'. Spent the rest of suppertime digesting the following/all of which contain the words "trigeminal cells" & are pepper sites: http://easyweb.easynet.co.uk/~gcaselton/chile/chil-txt.html http://www.fiery-foods.com/dave/taste9.html http://www.chillifarm.com/whats_hot/whats_hot.asp http://www.rnw.nl/special/en/html/chillies010716.html http://www.dreamwater.net/kimsworld/pepp-info.html http://www.bayoutraders.com/body_hotbites.html http://www.angelfire.com/journal2/chronicpainforum/archivespage8.html If Ya want to see the rest/go to this URL: http://www.google.com/search?hl=en&q=trigeminal+cells+pepper&btnG=Google+Sea rch Hope this helps, Paul PS As much as I hate to start a controversy, is it "irritates" or "stimulates"? Will let Merriam-Webster call it: Entry Word: irritate Function: verb Text: to excite to angry annoyance <his rude interruptions really irritated her> Synonyms aggravate, burn (up), exasperate, gall, get, grate, huff, inflame, nettle, peeve, pique, provoke, put out, rile, roil; ANNOY Entry Word: stimulate Function: verb Text: 1 Synonyms PROVOKE 4, excite, galvanize, innervate, innerve, motivate, move, pique, quicken, rouse Related Word enliven, vivify; activate, dynamize, energize, vitalize Idioms build a fire under, get one started (or moving) My opinion.....irriatate (Synonyms aggravate, burn (up), ) wins. From: "AndyB" <quark@erols.com> To: "dygurkem none" <dygurkem@hotmail.com> Subject: Re: [CH] Capsaicin Presentation > dygurkem none wrote: > > <snip> > > When you eat capsaicin, it irritates your trigeminal cells. > > It is more correct to say "stimulates", rather than "irritates". > > See: > http://antoine.frostburg.edu/chem/senese/101/features/capsaicin.shtml > > > Thank you, Jocelyn > > AndyB >