Chiles have the direct effect on the cardiovascular system of increasing peripheral circulation. This would have a net effect of decreasing systemic blood pressure. The induction of sweating also lowers the blood pressure by cooling the body & loss of water. That said, I think there could be arguement for a transient spike in the blood pressure immediately after eating very picante chiles due to the thrill of it all, ie.the body's release of epinephrine & norepinephrine. I recommend capsaicin containing supplements to my patients for many reasons, including maintaining good cardiovascular health. Joan E. Sullivan Owner & Pharmacist of Adobe Drug and Wellness Center