----- Original Message ----- From: Scott W. Schreiber <scottws@stratos.net> To: Chile Heads <chile-heads@globalgarden.com> Sent: Thursday, August 19, 1999 8:27 PM Subject: [CH] Toxic Capsaicin? > The question about the heart got me looking around...I found this: > SCIENCE/HEALTH ABSTRACTS > Vol. 5, No. 3 > Copyright 1986 Phylis Austin > CAPSAICIN TOXICITY > Capsaicin, found in various hot peppers, has adverse effects on the > peripheral nervous system. It also has adverse effects on several important > centers in the brain, and on enzyme and neuroprotein function in the brain. > Intestinal action on various nutrients, including protein, is altered to our > injury. Furthermore, the blood vessels and heart are particularly sensitive > to toxic factors in capsaicin. > > One dose of capsaicin is sufficient to destroy almost all substance P (an > important nerve chemical related to endorphins) in the dorsal root ganglia > of the nervous system, and causes about a 50 percent loss from part of the > spinal cord. Loss of substance P may also lead to urinary retention, and > because of the partial paralyzing effect on the bladder, is undoubtedly only > part of why peppers irritate the bladder and prostate. Even low doses lead > to low core body temperature (hypothermia), also due to a toxic influence on > the brain. Capsaicin also interferes with glucose uptake, and at least one > study suggests that it may cause cancer of the duodenum. (Nutrition Reviews > 44(1)20-23, January, 1986) An earlier report (Anticancer Research 4:117-120, > 1984) revealed the tumorigenic and mutagenic effect of capsaicin. > > http://www.tagnet.org/abstracts/search/v5/n3/v5n31.htm > > Scott > > Sounds like the best thing that Carp can do to get rid of his groundhog is to let him eat heartily in the pepper patch. I am positive that our co chile-head comrades will soon provide us with the kind of scientific studies that we like. Akiva