Okay, so what is considered "one dose"? This is an older article, does anyone know if there is any supporting research that has been done in the last ten years? Having been an editor for articles in a technical journal, I know of some of the unsupported cr@p that gets accepted for publication. I am not saying that is necessarily the case with this article, I just know to question validity and presentation. ...not like this article will change my chile habits anyway... Suz >One dose of capsaicin is sufficient to destroy almost all substance P (an >important nerve chemical related to endorphins) <snip>