I've had acid reflux for years. When I first tried Prilosec, it worked wonders, but the label said you could only use it for a short time. Then I struggled with OT meds and Tums, moving up to Tums Ultra (that's okay, I get calcium from them too). Finally my doctor said they had decided you could use Prilosec for a longer period of time than originally thought. So I took that for a few years. Okay, they finally came out with a generic version that seems to be working okay for me (our insurance pays for meds but I assume it's cheaper). But first...But first, the manufacturer of Prilosec, whose patent was about to run out made slight changes to the formula according to the sources I've read, then called and patented it as Nexium, and proceeded to sell it via television. What happens when that patent runs out? Lastium? It infuriated me (I know, some of you will say that's good business or the American way -- I say it's a violation of patient rights) that the manufacturer had people call me to "talk to me about my prescription." I told them I didn't buy from telemarketers and they kept saying they weren't selling anything, they just wanted to talk (about things they had no right to know). I'm extremely happy that the generic (Omeprazole) is working so well. @#$%^ multinational drug companies. Margaret L >Hello, again, George, > >I know what you mean: our kitchen cabinet is beginning to look like my >grandmother's, with those little amber plastic bottles. But truth be told, >I would be one sick puppy without my Nexium. > >One change I have made that has proved very beneficial is to drink tea >instead of coffee. The slight amount of caffein in it does not seem to >bother me. Give it a try. > >Ron